Selected Publications

  • Rovira Gonzalez YI, Moyer AL, LeTexier NJ, Bratti AD, Feng S, Sun C, Liu T, Mula J, Jha P, Iyer SR, Lovering RM, O'Rourke B, Noh HL, Suk S, Kim JK, Umanah GK, Wagner KR.  Mss51 deletion enhances muscle metabolism and glucose homeostasis in mice.  JCI Insight.  2019 Sept 17 [Epub ahead of print] PMID:  31527314.

  • Nance ME, Shi R, Hakim CH, Wasala NB, Yue Y, Pan X, Zhang T, Robinson CA, Duan SX, Yao G, Yang NN, Chen SJ, Wagner KR, Gersbach CA, Duan D.  AAV9 edits muscle stem cells in normal and dystrophic adult mice.  Mol Ther. 2019 Sept 4 [Epub ahead of print] PMID 31327755.

  • Gilbert-Honick J, Ginn B, Zhang Y, Salehi S, Wagner KR, Mao H-Q, Grayson WL.  Adipose-derived stem/stromal cells on electrospun fibrin microfiber bundles enable moderate muscle reconstruction in a volumetric muscle loss model.  Cell Transplantation. 2018  Oct 9 [Epub ahead of print].  PMID 30298751. 

  • Estrellas KM, Chung L, Cheu LA, Sadtler K, Majumdar S, Mula J, Wolf MT, Elisseeff JH, Wagner KR.  Biological scaffold-mediated delivery of myostatin inhibitor promotes a regenerative immune response in an animal model of Duchenne muscular dystrophy.   J Biol Chem 2018 Aug 23 [Epub ahead of print].  PMID 30139748.

  • Gilbert-Honick J, Iyer SR, Somers SM, Lovering RM, Wagner K, Mao HQ and Grayson WL.  Engineering functional and histological regeneration of vascularized skeletal muscle. Biomaterials 2018, 164: 70-79. PMID 29499437

  • Chen JCJ, King OD, Zhang Y, Clayton NP, Spencer C, Wentworth BM, Emerson CP*, Wagner KR*.  Morpholino-Mediated Knockdown of DUX4 Towards Facioscapulohumeral Muscular Dystrophy Therapeutics.  Molecular Therapy 2016, 24(8): 1405-11.PMID27387237. 

  • Choi IY, Lim H, Estrellas K, Mula J, Cohen T, Zhang Y, Donnelly C, Richard JP, Kin Y, Kim H, Kazuki Y, Oshimura M, Rothstein J, Maragakis N, Wagner KR*, Lee G*. Concordant but varied phenotypes among patient-specific myoblasts of Duchenne muscular dystrophy revealed by human iPSC-based model.  Cell Reports  2016, 15 (1): 2301-12. PMID 27239027.  

  • Choudhury SR, Fitzpatrick Z, Harris, AF, Maitland SA, Ferreira JS, Zhang Y, Ma S, Sharma RB, Ray-Edwards HL, Johnson JA, Johnson AK, Alonso LC, Punzo, C, Wagner KR, Maguire CA, Kotin RM, Martin DR, Sena-Esteves M.  In vivo selection yields AAV-B1 capsids for CNS and muscle gene therapy.  Mol Ther. 2016, 24(7): 1247-57.  PMID 27117222. 

  • Sadtler K, Estrellas K, Allen BW, Wolf MT, Fan H, Tam AJ, Patel C, Luber BS, Wang H, Wagner KR, Powell JD, Housseau F, Pardoll DM, Elisseeff JH.  Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells. Science 2016, 352(6283):  366-70. PMID 2708173.

  • Moyer AL, Wagner KR. Mammalian Mss51 is a skeletal muscle-specific gene modulating cellular metabolism. The Journal of Neuromuscular Diseases. 2015; 2(4): 371–385. PMID 26634192.

  • Cohen TV, Kollias HD, Liu N, Ward CW, Wagner KR. Genetic disruption of Smad7 impairs skeletal muscle growth and regeneration. The Journal of Physiology. 2015; 593(11): 2479-97. PMID: 25854148. 

  • Zhang Y, King OD, Rahimov F, et al. Human skeletal muscle xenograft as a new preclinical model for muscle disorders. Human Molecular Genetics. 2014;23(12):3180-3188. PMID: 24452336.

  • Miciak, J. J., Warsing, L. C., Tibbs, M. E., Jasper, J. R., Jampel, S. B., Malik, F. I., Tankersley, C. and Wagner, K. R. (2013), Fast skeletal muscle troponin activator in the dy2J muscular dystrophy model. Muscle Nerve, 48: 279–285. PMID: 2351272.

  • Rahimov F, King OD, Warsing LC, Powell RE, Emerson CP, Kunkel LM, Wagner KR. Gene expression profiling of skeletal muscles treated with a soluble activin type IIB receptor. Physiological Genomics. 2011; 43: 398-407. PMID: 21266502.

  • Li ZB, Zhang J, Wagner KR. Inhibiting myostatin reverses muscle fibrosis through apoptosis. Journal of Cell Science. 2012; 125(17): 3957-3965. PMID: 22685331. 

  • Rahimov F, King OD, Warsing LC, Powell RE, Emerson CP, Kunkel LM, Wagner KR.  Gene expression profiling of skeletal muscles treated with a soluble activin type IIB receptor.  Physiol Genomics. 2011; 43:398-407. PMID: 21266502

  • Li ZB, Kollias HD, Wagner KR. Myostatin directly regulates skeletal muscle fibrosis. Journal of Biological Chemistry. 2008; 283: 19371-19378. PMID: 18453534.